The Tuberculosis Vaccines Pipeline: A New Path to the Same Destination?
نویسنده
چکیده
Call it a paradigm shift, a pivot, or a turn – tuberculosis (TB) vaccine research and development (R&D) is entering a period of basic science. After years of focusing on phase II clinical trials, some of the field’s largest players are now redirecting attention and resources to the beginning of the pipeline – basic discovery and preclinical development. This change is motivated by a growing consensus that the guiding assumptions of the last 10 years of TB vaccine research require updating in the face of emerging evidence from the clinic and the lab.
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